منابع مشابه
Antifungal Prophylaxis in Immunocompromised Patients
Invasive fungal infections (IFIs) represent significant complications in patients with hematological malignancies. Chemoprevention of IFIs may be important in this setting, but most antifungal drugs have demonstrated poor efficacy, particularly in the prevention of invasive aspergillosis. Antifungal prophylaxis in hematological patients is currently regarded as the gold standard in situations w...
متن کاملCaspofungin as secondary antifungal prophylaxis and subsequent maintenance antifungal prophylaxis therapy in hematological malignancy patients.
AIM This study aimed to investigate the efficacy and safety of caspofungin as secondary antifungal prophylaxis (SAP) and subsequent maintenance therapy for SAP in hematological malignancy patients. METHODS Forty four patients receiving caspofungin for SAP and 43 patients not receiving any SAP agents during their subsequent chemotherapy or HSCT were reviewed retrospectively. The clinical chara...
متن کاملChoice of Antifungal Agent for Prophylaxis
Over the years, the different scientific societies have established a series of recommendations on antifungal prophylaxis based on prospective studies performed with different drugs1-6. Table 1 summarises these recommendations for the three situations in which fungal infection is most frequent: acute leukaemias, myelodysplastic syndromes and autologous and allogenic hematopoietic stem cell tran...
متن کاملAntifungal Prophylaxis for Adults with Leukemia
The risk for invasive fungal infections in patients with acute leukemia is generally low (4%–8%), and the routine use of fungal prophylaxis is not warranted except in specific high-risk groups that should be identified among this population. In a prophylactic study with a new agent, fluconazole or itraconazole oral solution represent good choices for the comparator because they are proven bette...
متن کاملAntifungal prophylaxis during neutropenia and immunodeficiency.
Fungal infections represent a major source of morbidity and mortality in patients with almost all types of immunodeficiencies. These infections may be nosocomial (aspergillosis) or community acquired (cryptococcosis), or both (candidiasis). Endemic mycoses such as histoplasmosis, coccidioidomycosis, and penicilliosis may infect many immunocompromised hosts in some geographic areas and thereby c...
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ژورنال
عنوان ژورنال: Annals of the American Thoracic Society
سال: 2021
ISSN: 2329-6933,2325-6621
DOI: 10.1513/annalsats.202103-300le